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Cocoa extract, multivitamin supplements do not lower fracture risk for older adults

Cocoa extract, multivitamin supplements do not lower fracture risk for older adults

Multivitamin and cocoa extract supplements do not protect against clinical fractures for older adults, according to data published in the Journal of Bone and Mineral Research.As Healio previously reported, the Cocoa Supplement and Multivitamin Outcomes Study (COSMOS) randomly assigned 21,442 adults aged 60 years and older participating in the Women’s Health Initiative extension study or …

GLP-1 agonists may be protective against hip fracture in patients with type 2 diabetes

GLP-1 agonists may be protective against hip fracture in patients with type 2 diabetes

SAN DIEGO — GLP-1 agonists may be protective against hip fracture when administered for the treatment of type 2 diabetes, according to results presented here.“This study supports other studies showing that GLP-1s can have a positive effect on bone mineral density by showing that patients that are treated with these have a lower incidence of …

Testosterone therapy significantly improves sexual desire in older men with prediabetes

Testosterone therapy significantly improves sexual desire in older men with prediabetes

Testosterone therapy plus lifestyle intervention was tied to a larger improvement in sexual desire than lifestyle intervention alone among older men with impaired glucose tolerance, according to a secondary analysis of the T4DM trial.As Healio previously reported, the T4DM trial randomly assigned 1,007 men aged 50 to 74 years with a waist circumference of 95 …

Little pacemakers ‘reliable’ in stabilizing newborns needing pacing

Little pacemakers ‘reliable’ in stabilizing newborns needing pacing

Miniaturized pacemakers were successfully implanted in infants and neonates requiring pacing and performed reliably until planned explant and/or replacement with a standard-sized device, researchers reported.Currently, standard pacemakers are too large for use in small neonates, and as a result, the complication rate can be as high as 25%, and include infection, erosion and migration of …

Hormone therapy use, duration not tied to brain tumor risk for menopausal women

Hormone therapy use, duration not tied to brain tumor risk for menopausal women

Among menopausal women, hormone therapy use and duration were not associated with brain malignancy risk, although researchers cautioned that more research is needed, according to findings published in Menopause.“The widespread use of HT is evident, with an estimated 600 million woman-years of HT usage recorded in Western countries over the past 50 years, beginning in …

CagriSema confers 15.7% weight loss at 68 weeks for adults with obesity, type 2 diabetes

CagriSema confers 15.7% weight loss at 68 weeks for adults with obesity, type 2 diabetes

Adults with obesity and type 2 diabetes receiving once-weekly combination cagrilintide 2.4 mg and semaglutide 2.4 mg lost 15.7% of their body weight at 68 weeks, according to topline data from the REDEFINE 2 trial.As Healio previously reported in December, CagriSema (Novo Nordisk) conferred a 22.7% weight loss at 68 weeks among adults with obesity …

Q&A: ‘Normal’ blood glucose may still increase risk for heart disease

Q&A: ‘Normal’ blood glucose may still increase risk for heart disease

Slightly elevated blood glucose within a range of what is generally considered “normal” may be associated with increased risk for heart disease, researchers reported.Gregg C. Fonarow, MD, FACC, FAHA, FHFSA, director of the Ahmanson-UCLA Cardiomyopathy Center, co-director of the UCLA Preventive Cardiology Program, co-chief of the division of cardiology at UCLA and Eliot Corday Chair …

NKF Spring Clinical Meetings to highlight hot topics for nephrology professionals

NKF Spring Clinical Meetings to highlight hot topics for nephrology professionals

The National Kidney Foundation Spring Clinical Meetings, taking place April 9 to 13, in Boston, will provide interprofessional attendees with the latest information on evolving areas of kidney care.With many important topics to cover and a fixed number of sessions available, the program committee prioritized advancements in science and clinical trials for common chronic kidney …

Q&A: ‘Normal’ blood glucose may still increase risk for heart disease

Q&A: ‘Normal’ blood glucose may still increase risk for heart disease

Slightly elevated blood glucose within a range of what is generally considered “normal” may be associated with increased risk for heart disease, researchers reported.Gregg C. Fonarow, MD, FACC, FAHA, FHFSA, director of the Ahmanson-UCLA Cardiomyopathy Center, co-director of the UCLA Preventive Cardiology Program, co-chief of the division of cardiology at UCLA and Eliot Corday Chair …

Jump rope an ‘effective, low-cost exercise’ for improving cardiorespiratory fitness

Jump rope an ‘effective, low-cost exercise’ for improving cardiorespiratory fitness

High-intensity interval exercise and moderate-intensity continuous exercise performed through rope skipping improved cardiorespiratory fitness in young adults, results from a randomized study revealed.The findings — published in European Journal of Clinical Nutrition — indicated that rope skipping, also known as jump rope, could be recommended by primary care providers “as an effective, low-cost exercise to …

NovoCare Pharmacy may improve access to Wegovy, but concerns about affordability remain

NovoCare Pharmacy may improve access to Wegovy, but concerns about affordability remain

Adults with obesity who have a prescription for Wegovy but do not have insurance coverage for the drug can now purchase the medication through a new Novo Nordisk direct-to-consumer program.In a March 5 press release, Novo Nordisk announced the launch of NovoCare Pharmacy, a direct-to-patient program that will provide any available dose of Wegovy (semaglutide, …

Tolvaptan may slow eGFR decline in patients with autosomal dominant PKD

Tolvaptan may slow eGFR decline in patients with autosomal dominant PKD

Routine use of tolvaptan in clinical practice may slow eGFR decline for patients with autosomal dominant polycystic kidney disease compared with historical controls, data show.“Efficacy of tolvaptan has been demonstrated in controlled clinical trials with highly motivated patients and regular follow-up at PKD centers of excellence,” Ronald D. Perrone, MD, FASN, professor of medicine at …

NovoCare Pharmacy may improve access to Wegovy, but concerns about affordability remain

NovoCare Pharmacy may improve access to Wegovy, but concerns about affordability remain

Adults with obesity who have a prescription for Wegovy but do not have insurance coverage for the drug can now purchase the medication through a new Novo Nordisk direct-to-consumer program.In a March 5 press release, Novo Nordisk announced the launch of NovoCare Pharmacy, a direct-to-patient program that will provide any available dose of Wegovy (semaglutide, …

AI could assist early, rapid diagnosis of asymptomatic heart failure

AI could assist early, rapid diagnosis of asymptomatic heart failure

AI-assisted diagnosis of asymptomatic left ventricular dysfunction may detect disease early and thereby expedite treatment of low ejection fraction, according to data published in JACC: Advances.“Early detection of left ventricular dysfunction is crucial, as delayed diagnosis often leads to worse patient outcomes and higher health care costs,” Salima Qamruddin, MD, technical director of the echocardiography …

NovoCare Pharmacy may improve access to Wegovy, but concerns about affordability remain

NovoCare Pharmacy may improve access to Wegovy, but concerns about affordability remain

Adults with obesity who have a prescription for Wegovy but do not have insurance coverage for the drug can now purchase the medication through a new Novo Nordisk direct-to-consumer program.In a March 5 press release, Novo Nordisk announced the launch of NovoCare Pharmacy, a direct-to-patient program that will provide any available dose of Wegovy (semaglutide, …

Incidence rate of PE-related hospitalizations low in pediatric population

Incidence rate of PE-related hospitalizations low in pediatric population

The incidence rate of pulmonary embolism-related hospitalizations in pediatric patients revealed that this outcome occurred infrequently; however, having acute PE raised the odds for in-hospital mortality, according to study findings.“Acute PE is rare but has a high risk of in-hospital death,” Simon Wolf, MMed, research assistant at University Hospital Zurich and PhD candidate at Leiden …

Makary vows FDA will uphold ‘gold standard of trusted science’ during senate hearing

Makary vows FDA will uphold ‘gold standard of trusted science’ during senate hearing

Key takeaways:Lawmakers grilled Martin Makary, MD, MPH, on transparency, his plans for mifepristone and his stance on the recently cancelled Vaccine Advisory Committee meeting during Thursday’s senate hearing to be the next FDA commissioner.Makary, a surgeon and public policy researcher at Johns Hopkins University, has been nominated to be the agency’s next leader under the …

Makary vows FDA will uphold ‘gold standard of trusted science’ during senate hearing

Makary vows FDA will uphold ‘gold standard of trusted science’ during senate hearing

Key takeaways:Lawmakers grilled Martin Makary, MD, MPH, on transparency, his plans for mifepristone and his stance on the recently cancelled Vaccine Advisory Committee meeting during Thursday’s senate hearing to be the next FDA commissioner.Makary, a surgeon and public policy researcher at Johns Hopkins University, has been nominated to be the agency’s next leader under the …

Makary vows FDA will uphold ‘gold standard of trusted science’ during senate hearing

Makary vows FDA will uphold ‘gold standard of trusted science’ during senate hearing

Key takeaways:Lawmakers grilled Martin Makary, MD, MPH, on transparency, his plans for mifepristone and his stance on the recently cancelled Vaccine Advisory Committee meeting during Thursday’s senate hearing to be the next FDA commissioner.Makary, a surgeon and public policy researcher at Johns Hopkins University, has been nominated to be the agency’s next leader under the …

Replacing butter with plant-based oil may have ‘significant long-term health benefits’

Replacing butter with plant-based oil may have ‘significant long-term health benefits’

Adults who consume a large amount of butter have a 15% greater mortality risk, according to an analysis published in JAMA Internal Medicine.But, opting to replace this consumption with plant-based oils instead could significantly lower the risk for death from all causes and cancer.“Primary care providers might consider advising patients to reduce butter intake and …

Thyroid cancer incidence plateaued during 2010s after rising from 1975 to 2009

Thyroid cancer incidence plateaued during 2010s after rising from 1975 to 2009

After rising over a 35-year period, thyroid cancer incidence in the U.S. plateaued from 2010 to 2019, according to findings published in The Lancet Diabetes & Endocrinology.In a retrospective analysis of data from the National Cancer Institute’s Surveillance, Epidemiology and End Results (SEER) and National Center for Health Statistics databases, researchers found no changes in …